IL-18 and Lower Risk for Lung Cancer: Triangulated Evidence from Germline Predictions, Pre-Diagnostic Measurements, and Tumor Expression
Karl Smith-Byrne, Yan Chen, Linda Kachuri, Pooja M. Kapoor, Florence Guida, Hana Zahed, Karine Alcala, Christopher Ian Amos, Joshua Ronald Atkins, Barbara Bodinier, Aida Ferreiro-Iglesias, Rayjean J. Hung, Mikael Johansson, Woon‐Puay Koh, Cecilie Kyrø, , Anders Mälarstig
This study identifies IL-18 as a biomarker for reduced lung cancer risk using genetic, pre-diagnostic, and tumor expression data, with potential therapeutic implications.
medRxiv · Mar 26, 2021 · PreprintGenetic & Genomic Medicine