Author

Yan Chen

Karolinska InstitutetORCID 0000-0003-3516-9546Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yan Chen15 papers · Chinese Academy of Sciences

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aida Ferreiro-IglesiasiD· 1 shared Amulya SreekumariD· 1 shared Anders MälarstigiD· 1 shared Arnulf LanghammeriD· 1 shared Barbara BodinieriD· 1 shared Brian Benz· 1 shared Cecilie KyrøiD· 1 shared Chengqin WangiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Aida Ferreiro-IglesiasORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 28, 2026

Loss of Ferroptosis-suppressors Accelerates Breast Cancer Recurrence by Promoting Dormancy Exit

Emily K. Shea, Matthew Lawrence-Paul, Amulya Sreekumar…·Lewis A. Chodosh

This study identifies PNPLA2, GOT1, and GPX4 as ferroptosis-suppressors whose loss accelerates breast cancer recurrence by promoting dormancy exit and enhancing ferroptosis resistance in dormant cells.

DOI 10.64898/2026.10.22.761187

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Cell BiologyBiophysics ReportsPeer-reviewedJan 1, 2024

Screening for metastasis-related genes in mouse melanoma cells through sequential tail vein injection

Qinggang Hao, Rui Dong, Weiyu Bai…·Jianwei Sun

This study screens for metastasis-related genes in mouse melanoma cells using sequential tail vein injection and identifies differentially expressed genes associated with metastasis.

3 citations

mousebulk RNA-seq

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Genetic & Genomic MedicinemedRxivPreprintMar 26, 2021

IL-18 and Lower Risk for Lung Cancer: Triangulated Evidence from Germline Predictions, Pre-Diagnostic Measurements, and Tumor Expression

Karl Smith-Byrne, Yan Chen, Linda Kachuri…·Anders Mälarstig

This study identifies IL-18 as a biomarker for reduced lung cancer risk using genetic, pre-diagnostic, and tumor expression data, with potential therapeutic implications.

2 citations

humanGWAS summary statistics

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