Woon‐Puay Koh

This study shows that better adherence to the DASH diet in midlife and early elderhood improves late-life verbal memory and brain health through structural and neurovascular mechanisms.

This paper introduces DELSSOME, a deep learning framework that accelerates biophysical brain circuit model optimization, enabling faster parameter estimation and lifespan trajectory analysis of cortical E/I ratios.

The paper identifies DNA methylation biomarkers predictive of Type-2 diabetes in Asian populations and shows their utility in risk stratification.

The paper analyzes gut metagenomes of Asian octogenarians to identify age-related microbial shifts and their associations with aging phenotypes.

This paper evaluates polygenic risk scores for predicting common cancers in East Asians using a large cohort, finding significant risk stratification for breast, prostate, and colorectal cancers.

RAPTOR provides a secure, cloud-native genomics repository with a five-safes framework to ensure compliance and data protection for genomic research.

This study identifies IL-18 as a biomarker for reduced lung cancer risk using genetic, pre-diagnostic, and tumor expression data, with potential therapeutic implications.