Author

Pranav Kantroo

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:protein sequence· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:protein design· 1 Research Focus:sequence-to-function modeling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Benjamin B. MachtaiD· 2 shared Günter P. WagneriD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Benjamin B. MachtaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pseudo-perplexity in One Fell Swoop for Protein Fitness Estimation

Pranav Kantroo, Günter P. Wagner, Benjamin B. Machta

The paper introduces a method to estimate protein fitness using pseudo-perplexity from a single forward pass through a language model, achieving state-of-the-art results on a benchmark.

PRX Life · Jul 25, 2025Peer-reviewedBioinformatics

High fitness paths can connect proteins with low sequence overlap

Pranav Kantroo, Günter P. Wagner, Benjamin B. Machta

This paper develops an algorithm to generate viable sequence paths between distantly related proteins, using ESM2 to evaluate fitness and maintain high viability through single residue changes.

bioRxiv · Nov 13, 2024 · PreprintBioinformatics