Benjamin B. Machta

The paper shows that membrane prewetting enhances biopolymer condensation by lipid composition, observed in simulations, reconstitution, and cells.

The paper models how membrane phase transitions affect protein-protein interaction networks, showing sensitivity to thermodynamic parameters near critical points.

The paper introduces a method to estimate protein fitness using pseudo-perplexity from a single forward pass through a language model, achieving state-of-the-art results on a benchmark.

The paper investigates how hair cells in the cochlea tune resonant modes to the edge of instability without destabilizing collective modes using a computational model.

This paper develops an algorithm to generate viable sequence paths between distantly related proteins, using ESM2 to evaluate fitness and maintain high viability through single residue changes.

The paper shows E. coli chemosensing is limited by internal noise, not physical molecule diffusion limits, using information rate analysis.

This paper introduces a new model of E. coli chemosensory lattice signal processing called lattice ultrasensitivity, which achieves high gain without requiring fine-tuning.

The paper shows that polymer collapse and liquid-liquid phase-separation are coupled in a generalized prewetting transition, using simulations and theory to demonstrate stability in regimes where individual phases are unstable.