Expression variation analysis for tumor heterogeneity in single-cell RNA-sequencing data
Emily F. Davis-Marcisak, Pranay Orugunta, Genevieve Stein-O’Brien, Sidharth V. Puram, Evanthia T. Roussos Torres, Alexander C. Hopkins, Elizabeth M. Jaffee, Alexander V. Favorov, Bahman Afsari, Loyal A. Goff, Elana Judith Fertig
This paper introduces EVAsc, a method to analyze expression variation in scRNA-seq data to quantify tumor heterogeneity across cell types, subtypes, and patients.
bioRxiv · Nov 27, 2018 · PreprintBioinformatics