Loss of PRMT2 in myeloid cells in normoglycemic mice phenocopies impaired regression of atherosclerosis in diabetic mice
Beyza Vurusaner, Prashanth Thevkar-Nages, Ravneet Kaur, Chiara Giannarelli, Michael J. Garabedian, Edward A A Fisher
The paper shows that loss of PRMT2 in myeloid cells impairs atherosclerosis regression in normoglycemic mice, mimicking diabetic conditions, through increased inflammation and macrophage dysfunction.
Scientific Reports · Jul 14, 2022Peer-reviewedGenetics