Michael J. Garabedian

This study shows YAP/TAZ inhibition selectively reduces pro-fibrotic TGF-β signaling in vocal fold fibroblasts, preventing fibrosis in a rat model.

This study identifies CHREBP and NF-kappa B as regulators of ACSL1 expression in macrophages under hyperglycemia and inflammation.

The paper shows that loss of PRMT2 in myeloid cells impairs atherosclerosis regression in normoglycemic mice, mimicking diabetic conditions, through increased inflammation and macrophage dysfunction.

This study shows that inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and improves atherosclerosis and obesity by altering macrophage and adipose tissue gene expression.

The paper shows that BDNF-dependent GR phosphorylation is essential for maintaining learning-induced synapses and memory retention in mice.

This study shows that phosphorylation of LXRα affects atherosclerosis regression by altering macrophage trafficking in diabetic mice.

This study shows that preventing LXRα phosphorylation at Ser196 reduces hepatic inflammation and fibrosis in mice on a high-fat diet, revealing a novel role for LXR phosphorylation in diet-induced transcriptome changes.