Sequestration of oxidative is necessary but not sufficient enough to conclude dopaminergic neuroprotective efficacy of curcumin: Insights from ALSS Drosophila Parkinson disease model
Limamanen Phom, Priyanka Modi, Abhik Das, Sarat C. Yenisetti
The paper shows curcumin reduces oxidative stress in both healthy and transition stages of Drosophila Parkinson's model but only protects neurons during the healthy phase, highlighting the need to study molecular mechanisms beyond oxidative stress.
bioRxiv · Sep 19, 2024 · PreprintNeuroscience