Performance comparison of probe-capture enrichment sequencing of viruses in wastewater influent and settled solids from the California Central Valley
Amit Lavon, Julian M. Pender, Rachel Olson, Titash Chatterjee, Colleen C. Naughton, Priyanka Prashar, Scott Kuersten, Jonathan A. Eisen, Katrine Whiteson, Heather N. Bischel
The paper compares two viral sequencing pipelines from wastewater influent and solids, finding that solids capture more DNA viruses while influent captures more RNA viruses, with probe-capture enrichment providing comparable results across fractions.
bioRxiv · Oct 9, 2026 · PreprintGenomics