Scott Kuersten

The paper compares two viral sequencing pipelines from wastewater influent and solids, finding that solids capture more DNA viruses while influent captures more RNA viruses, with probe-capture enrichment providing comparable results across fractions.

RiboZAP designs custom rRNA depletion probes from metatranscriptomic data without prior knowledge of sample composition, improving mRNA recovery and transcriptome coverage.

The paper improves rRNA depletion for mouse cecal metatranscriptome analysis by designing probes based on sequence abundance rather than taxonomy, increasing mRNA reads and reducing bias.

The paper studies how different introns respond to splicing inhibitors in a humanized yeast strain, revealing intron-specific sensitivity and the impact of BP sequence variation.

The paper introduces a probe set for efficient rRNA depletion in human microbiome samples, improving metatranscriptomic analysis and reducing quantitative error.

The paper evaluates RNA purification kits and blood collection tubes for exRNA quality, finding that preservation tubes and purification methods significantly affect RNA stability, sensitivity, and reproducibility.

The paper creates a comprehensive atlas of RNA transcriptomes across 20 human biofluids, revealing significant differences in RNA concentration and composition, and validates potential biomarkers in disease cohorts.

The paper presents a comprehensive human transcriptome atlas with single-nucleotide resolution, identifying thousands of novel RNA species and regulatory interactions.

This study investigates the role of the GLD-1-FOG-2 complex in regulating C. elegans hermaphrodite spermatogenesis through multiple RNA-binding interactions and quantitative modeling.

The paper quantifies gene expression regulation at multiple layers in response to ER stress in cervical cancer cells over time, identifying shared and stress-specific regulatory events.