Author

Q. Shangguan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein structure prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

M. F. White· 2 shared R. Sundaramoorthy· 1 shared S. Graham· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersMicrobiology

M. F. White

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2 papers

Recent·Most cited

Repurposing the atypical Type I-G CRISPR system for bacterial genome engineering

Q. Shangguan, M. F. White

This study repurposes the type I-G CRISPR system for bacterial genome engineering, showing that Cas3 helicase activity is not essential for immunity and that the system can improve homology-directed repair efficiency.

bioRxiv · Apr 24, 2023Microbiology

Structure and mechanism of the type I-G CRISPR effector

Q. Shangguan, S. Graham, R. Sundaramoorthy, M. F. White

This study reports the structure and function of the type I-G CRISPR effector from Thioalkalivibrio sulfidiphilus, revealing key molecular details about its composition and mechanism.

bioRxiv · Aug 8, 2022Microbiology