Author

Q. V. Van

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

D. A. Nissley· 1 shared E. P. O'Brien· 1 shared I. Sitarik· 1 shared L. P. Dang· 1 shared M. S. Li· 1 shared Y. A. Jiang· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

D. A. Nissley

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1 paper

Recent·Most cited

Synonymous mutations can alter protein dimerization through localized interface misfolding involving self-entanglements

L. P. Dang, D. A. Nissley, I. Sitarik, Q. V. Van, Y. A. Jiang, M. S. Li, E. P. O'Brien

This paper shows synonymous mutations can alter protein dimerization by causing misfolded self-entangled states that disrupt dimer interfaces, with effects dependent on translation speed.

bioRxiv · Oct 26, 2021Biophysics