M. S. Li

Serotonin Promotes Vesicular Association and Fusion by Modifying Lipid Bilayers

This study shows serotonin enhances vesicle association and fusion with lipid bilayers by altering their mechanical properties through water content changes.

A Newly Identified Class of Protein Misfolding in All-atom Folding Simulations Consistent with Limited Proteolysis Mass Spectrometry

The paper identifies entangled misfolded states in all-atom protein folding simulations that resemble native states and are consistent with mass spectrometry data.

Synonymous mutations can alter protein dimerization through localized interface misfolding involving self-entanglements

This paper shows synonymous mutations can alter protein dimerization by causing misfolded self-entangled states that disrupt dimer interfaces, with effects dependent on translation speed.

Ribosome elongation kinetics of consecutively charged residues are coupled to electrostatic force

The paper shows charged residues affect ribosome elongation speed through mechanochemical forces, supported by simulations and experimental data.

A computational model to unravel the function of amyloid-β peptide in contact with a phospholipid membrane

This paper uses a computational model to show that monomeric amyloid-β peptide reduces interactions between divalent cations and phospholipid membranes, potentially protecting synaptic structures.

Mechanical and thermodynamic properties of Aβ42, Aβ40 and α-synuclein fibrils: A coarse-grained method to complement experimental studies

This study uses molecular dynamics simulations to analyze the mechanical and thermodynamic properties of Aβ40, Aβ42, and α-synuclein fibrils, showing elastic anisotropy and mechanostability differences.