A bifunctional kinase-phosphatase module integrates mitotic checkpoint and error-correction signalling to ensure mitotic fidelity
A. Corno, M. H. Cordeiro, L. A. Allan, Q. W. Lim, E. Harrington, R. J. Smith, A. T. Saurin
This study shows that the PLK1-PP2A kinase-phosphatase pair regulates mitotic checkpoint and error-correction signaling through feedback on the BUB complex, ensuring proper chromosome segregation.
bioRxiv · May 22, 2022Cell Biology