Cold protection allows local cryotherapy in a clinical-relevant model of traumatic optic neuropathy
Yikui Zhang, Mengyun Li, Bo Yu, Shengjian Lu, Lujie Zhang, Senmiao Zhu, Zhonghao Yu, Tian Xia, Haoliang Huang, WenHao Jiang, Si Zhang, Lanfang Sun, Qian Ye, Jiaying Sun, Hui Zhu, , Wencan Wu
This paper develops a cold-protective treatment for traumatic optic neuropathy using a clinically relevant animal model, showing that combined hypothermia and cold protection reduces inflammation and metabolic stress without cellular damage.
eLife · Mar 30, 2022Peer-reviewedNeuroscience