How the AFF1/4 scaffold recruits the elongation factor ELL2 to promote HIV-1 proviral transcription
Shiqian Qi, Zichong Li, Ursula Schulze-Gahmen, Goran Stjepanovic, Qiang Zhou, James Hurley
This study determines the crystal structure of the ELL2 C-terminal domain bound to AFF4, revealing its role in HIV-1 proviral transcription.
bioRxiv · Aug 6, 2016Biochemistry