Qiang Zhou

This study identifies HNK's mechanism of action through astrocytic μ-δ opioid receptor heterodimerization, showing it restores these heterodimers and produces rapid antidepressant effects.

This study shows that the rostral prelimbic cortex's excitation/inhibition balance modulates passive coping behavior, which is affected by chronic stress and reversed by the fast-acting antidepressant HNK.

This study investigates how retrieved memories direct behavior by showing how transient and sustained neurons in the dmPFC interact with the locus coeruleus to modulate freezing responses to conditioned threats.

The paper identifies specific neuronal subtypes in pediatric FCD that show significant transcriptomic alterations linked to drug-resistant epilepsy and suggests potential therapeutic targets.

This study shows that NMDA receptors bidirectionally modulate intrinsic excitability in inhibitory neurons, with extrasynaptic receptors playing a significant role.