Synthetic BiologybioRxivPreprint
A Divergent Class of Arylamine N-Acetyltransferases Catalyzes Convergent Amidative Condensation of Polyketides in Manumycins Biosynthesis
Yan Gao, Baodi Ma, Qiaqia Zhou…·Xudong Qu
The paper identifies a novel class of arylamine N-acetyltransferases that catalyze amidative condensation of polyketides, enabling new strategies for combinatorial biosynthesis of polyketide amides and manumycin derivatives.
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