Machine learning cross-platform proteomic imputation enables protein quality scoring and replication of epidemiological associations
Linke Li, Ahmed Alaa, Youxin Tan, İlker Demirel, Sam Freesun Friedman, Qiayi Zha, Russell P. Tracy, Kent D. Taylor, Bing Yu, Christie Mitchell Ballantyne, Rajat Deo, Ruth F. Dubin, Michael Y. Tsai, Gina Marie Peloso, Jennifer A. Brody, , Zhi Yu
This paper develops a machine learning framework to impute cross-platform proteomic data, improving replication of epidemiological findings and protein quality scoring.
bioRxiv · May 9, 2026 · PreprintBioinformatics