The holdase function of Escherichia coli Hsp70 (DnaK) chaperone
Ricksen S. Winardhi, Qingnan Tang, Huijuan You, Michael P. Sheetz, Jie Yan
This study investigates the holdase function of Escherichia coli DnaK chaperone using single-molecule assays, showing it stabilizes unfolded proteins and switches between holding and releasing states upon ATP binding.
bioRxiv · Apr 21, 2018 · PreprintMolecular Biology