BACH1 promotes hepatocellular carcinoma progression by targeting PDP1 towards the PI3K-AKT-mTOR signaling activation
Qiqi Bu, Xiaojing Qi, Qing Wang, Shujuan Liu, Shanshan Lin, Zhanhang Wang, Yiguo Zhang
This study identifies BACH1 as a tumor-promoting factor in hepatocellular carcinoma by activating the PI3K-AKT-mTOR pathway through PDP1 upregulation.
Bioorganic Chemistry · Oct 31, 2025Peer-reviewedBioengineering