Male mice with large inversions or deletions of X-palindrome arms are fertile and express their associated genes post-meiosis.
Alyssa N. Kruger, Quinn Ellison, Michele A. Brogley, Emma R. Gerlinger, Jacob L. Mueller
The paper investigates whether palindromic structures on the X chromosome are necessary for post-meiotic gene expression and fertility in male mice, finding that gene expression and fertility are unaffected by deletions of these regions.
Scientific Reports · Jun 6, 2018Peer-reviewedGenetics