Michele A. Brogley

Genomic structure, evolutionary origins, and reproductive function of a large amplified intrinsically disordered protein gene on the X chromosome (Laidx) in mice.

The paper identifies a large amplified intronless gene, Laidx, on the X chromosome in mice, shows its evolutionary origin from a horizontal gene transfer, and finds no reproductive defects in its absence.

Male mice with large inversions or deletions of X-palindrome arms are fertile and express their associated genes post-meiosis.

The paper investigates whether palindromic structures on the X chromosome are necessary for post-meiotic gene expression and fertility in male mice, finding that gene expression and fertility are unaffected by deletions of these regions.