Author

Quoc Nguyen

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Organism:mouse· 2 Research Focus:software / tool· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Aimin Yan· 2 shared Cristina Baricordi· 2 shared Luca BiascoiD· 2 shared Luigi Barbarossa· 2 shared Mariana LoperfidoiD· 2 shared Charles BroadbentiD· 1 shared Chris MasoniD· 1 shared Eric AlexanderiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBioinformatics

Aimin Yan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CTFacTomo: Reconstructing 3D Spatial Structures of RNA Tomography Transcriptomes by Collapsed Tensor Factorization

Tianci Song, Quoc Nguyen, Charles Broadbent, Rui Kuang

CTFacTomo reconstructs 3D spatial gene expressions from RNA tomography data using tensor factorization and regularization, outperforming benchmarks on zebrafish and mouse datasets.

PLoS Computational Biology · Mar 13, 2026Peer-reviewedBioinformatics

Analyzing and Visualizing Distance Measures for Clonal Trees

Thea Traw, Quoc Nguyen, Layla Oesper, Eric Alexander

This work defines four classes of clonal tree differences, analyzes them with three distance measures, and introduces a visualization tool to better understand tree comparisons.

bioRxiv · Jul 18, 2025 · PreprintBioinformatics

IS-Seq: a bioinformatics pipeline for integration sites analysis with comprehensive abundance quantification methods

Aimin Yan, Cristina Baricordi, Quoc Nguyen, Luigi Barbarossa, Mariana Loperfido, Luca Biasco

IS-Seq is a bioinformatics pipeline that integrates UMI-based and other methods for IS abundance estimation, showing UMI provides better accuracy than sonication fragment counts in clinical scenarios.

BMC Bioinformatics · Jul 18, 2023Peer-reviewedBioinformatics

Genetically engineered microglia-like cells have therapeutic potential for neurodegenerative disease

Robert N. Plasschaert, Mark P. DeAndrade, Fritz Hull, Quoc Nguyen, Tara Peterson, Aimin Yan, Mariana Loperfido, Cristina Baricordi, Luigi Barbarossa, John K. Yoon, Yildirim Dogan, Zeenath Unnisa, Jeffrey W. Schindler, Niek Peter van Til, Luca Biasco, Chris Mason

This study shows genetically engineered microglia-like cells can provide therapeutic protein levels in mouse models of neurodegenerative diseases.

bioRxiv · Sep 16, 2021 · PreprintNeuroscience