A non-canonical role for UPRER during heat stress in C. elegans.
Athena Alcala, Toni Castro Torres, R Barahona, Phillip Andrew Frankino, Ryo Higuchi‐Sanabria, Gilberto Garcia
This study shows heat stress activates UPRER through XBP-1 and HSF-1 in C. elegans, with cross-talk to cytosolic HSR and inter-tissue stress communication enhancing thermotolerance.
G3 Genes Genomes Genetics · Jun 22, 2026Peer-reviewedGenetics