The Hsp60 C-terminus Senses Substrate and Triggers Allosteric ATP Hydrolysis
D. H. Von Salzen, A. Rodriguez, A. Ullah, R. A. Bernal
This study shows that the C-terminal tail of Hsp60 senses substrate and triggers allosteric ATP hydrolysis, revealing the mechanism of substrate-dependent ATP hydrolysis in the chaperonin.
bioRxiv · Sep 15, 2023 · PreprintBiochemistry