NLRP3 and NLRP1/CARD8 pathways differently contribute to pyroptosis of CD8+ T cells of ART-treated HIV patients
M. E. G. V. Roa, R. A. G. Cambu, S. M. Yamada, V. C. Leal, A. Pontillo
This study investigates the role of NLRP3 and NLRP1/CARD8 inflammasome pathways in CD8+ T cell pyroptosis in ART-treated HIV patients, finding differential activation and resistance to pyroptosis.
bioRxiv · May 15, 2023 · PreprintImmunology