Author

A. Pontillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. F. de Brito· 1 shared A. N. Weber· 1 shared B. Danker· 1 shared B. Grimbacher· 1 shared C. L. Greve· 1 shared D. E. P. Souto· 1 shared D. Mendes· 1 shared D. S. de Lima· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. F. de Brito

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Author profile →

3 papers

Recent·Most cited

BTK and MMP9 regulate NLRP3 inflammasome-dependent cytokine and NET responses in primary neutrophils.

V. N. C. Leal, F. Bork, J. C. von Guilleaume, C. L. Greve, S. Bugl, B. Danker, Z. A. Bittner, B. Grimbacher, A. Pontillo, A. N. Weber

This paper shows that BTK and MMP-9 negatively regulate NLRP3 inflammasome activity in neutrophils, affecting cytokine and NET release.

bioRxiv · Feb 23, 2024Immunology

NLRP3 and NLRP1/CARD8 pathways differently contribute to pyroptosis of CD8+ T cells of ART-treated HIV patients

M. E. G. V. Roa, R. A. G. Cambu, S. M. Yamada, V. C. Leal, A. Pontillo

This study investigates the role of NLRP3 and NLRP1/CARD8 inflammasome pathways in CD8+ T cell pyroptosis in ART-treated HIV patients, finding differential activation and resistance to pyroptosis.

bioRxiv · May 15, 2023 · PreprintImmunology

Sensing soluble uric acid by Naip1-Nlrp3 platform

T. T. Braga, M. R. Davanso, D. Mendes, T. A. Souza, A. F. de Brito, M. C. Cruz, M. I. Hiyane, D. S. de Lima, V. Nunes, J. d. F. Giarola, D. E. P. Souto, T. Prochnicki, M. Lauterbach, S. M. P. Biscaia, R. A. de Freitas, , N. O. S. Camara

The paper investigates how soluble uric acid is sensed by the Naip1-Nlrp3 inflammasome platform in murine macrophages and shows its role in IL-1β production and inflammation.

bioRxiv · May 15, 2020Immunology