R. C. Koehler

Transcranial photoacoustic characterization of neurovascular physiology during early-stage photothrombotic stroke in neonatal piglets in vivo

This study uses transcranial photoacoustic imaging to detect early-stage photothrombotic stroke in neonatal piglets, finding that HbO2 saturation can distinguish affected from control brain regions.

Light-emitting diode-based transcranial photoacoustic measurement of sagittal sinus oxyhemoglobin saturation in hypoxic neonatal piglets

This study develops an LED-based transcranial photoacoustic method to measure oxyhemoglobin saturation in neonatal piglets under hypoxia, achieving low error rates for potential clinical monitoring.