R. Ciccocioppo

Cebranopadol, a novel long-acting opioid agonist with low abuse liability, to treat opioid use disorder: Preclinical evidence of efficacy

This study evaluates cebranopadol's efficacy and abuse liability in treating opioid use disorder using rat models, showing reduced self-administration and stress-induced reinstatement compared to heroin.

Network-Based Discovery of Opioid Use Vulnerability in Rats Using the Bayesian Stochastic Block Model

The paper identifies three distinct behavioral sub-populations in rats with varying opioid vulnerability using a Bayesian stochastic block model.