UHRF1-SRA recognizes symmetric non-CG methylated DNA through dual-flip out of 5-methyl cytosines
N. K. Nakarakanti, S. Abhishek, W. Deeksha, R. Eerappa
This study shows UHRF1 SRA recognizes non-CG methylated DNA through a dual-flip mechanism, with different binding affinities for mCHG and mCG.
bioRxiv · Dec 17, 2019 · PreprintBiophysics