In vitro and in silico modeling of cellular and matrix-related changes during the early phase of osteoarthritis
M.-C. Weber, L. Fischer, A. Damerau, I. Ponomarev, M. Pfeiffenberger, T. Gaber, S. Goetschel, J. Lang, S. Roeblitz, F. Buttgereit, R. Ehrig, A. Lang
This study combines in vitro and in silico models to simulate early osteoarthritis changes, showing inflammation-induced matrix degradation and partial reversibility.
bioRxiv · Aug 5, 2019Bioengineering