Author

A. Damerau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Lang· 3 shared F. Buttgereit· 3 shared M. Pfeiffenberger· 3 shared T. Gaber· 3 shared I. Ponomarev· 2 shared P. Hoff· 2 shared A. E. Hauser· 1 shared A. Hombrouck· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioengineering

A. Lang

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Author profile →

4 papers

Recent·Most cited

Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2

L. Ehlers, M. Wouters, A. Hombrouck, B. Pillay, S. Delafontaine, G. Bucciol, M. Baggio, M. Dzhus, E. Frances Rabanal, A. Damerau, J. Neugebauer, F. Ebstein, M. Jacquemyn, L. De Somer, R. Schrijvers, , I. Meyts

The paper identifies an intracellular hypoglycosylated form of ADA2 absent in DADA2 patients, linking its absence to reduced deaminase activity and variant pathogenicity.

bioRxiv · Oct 25, 2023 · PreprintImmunology

HIF-stabilization prevents delayed fracture healing

A. Lang, S. Helfmeier, J. Stefanowski, A. Kuppe, V. Sunkara, M. Pfeiffenberger, A. Wolter, A. Damerau, S. Hemmati-Sadeghi, J. Ringe, R. Haag, A. E. Hauser, M. Loehning, C. Perka, G. N. Duda, , F. Buttgereit

This study shows that stabilizing HIF-1α with deferoxamine and macrophage migration inhibitory factor improves fracture healing in a mouse model by enhancing calcification, osteogenic differentiation, and vascularization.

bioRxiv · Jul 2, 2020Bioengineering

An in vitro human-based fracture gap model - Mimicking the crosstalk between bone and immune cells

M. Pfeiffenberger, A. Damerau, I. Ponomarev, C. H. Bucher, Y. Chen, D. Barnewitz, C. Thoene-Reineke, P. Hoff, F. Buttgereit, T. Gaber, A. Lang

This study develops an in vitro 3D fracture gap model that mimics bone-immune cell interactions to study fracture healing mechanisms and therapeutic responses.

bioRxiv · Jun 26, 2020Bioengineering

In vitro and in silico modeling of cellular and matrix-related changes during the early phase of osteoarthritis

M.-C. Weber, L. Fischer, A. Damerau, I. Ponomarev, M. Pfeiffenberger, T. Gaber, S. Goetschel, J. Lang, S. Roeblitz, F. Buttgereit, R. Ehrig, A. Lang

This study combines in vitro and in silico models to simulate early osteoarthritis changes, showing inflammation-induced matrix degradation and partial reversibility.

bioRxiv · Aug 5, 2019Bioengineering