New targets for drug design: Importance of nsp14/nsp10 complex formation for the 3'-5' exoribonucleolytic activity on SARS-CoV-2
M. Saramago, C. Barria, V. Costa, C. S. Souza, S. C. Viegas, S. Domingues, D. Lousa, C. M. Soares, C. M. Arraiano, R. G. Matos
This study characterizes the nsp14-nsp10 complex in SARS-CoV-2, showing its role in ExoN activity and identifying potential drug targets.
The FEBS Journal · Apr 28, 2021Peer-reviewedMicrobiology