Author

R. J. Beck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

N. Andor· 2 shared G. J. Kimmel· 1 shared P. M. Altrock· 1 shared S. Bakhoum· 1 shared T. Veith· 1 shared X. Yu· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

N. Andor

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Author profile →

2 papers

Recent·Most cited

Local Adaptive Mapping of Karyotype Fitness Landscapes

R. J. Beck, N. Andor

This paper introduces ALFA-K, a method to infer karyotype fitness landscapes from single-cell data, revealing insights into aneuploidy evolution and environmental influences on fitness.

bioRxiv · Jul 14, 2023 · PreprintCancer Biology

Intra-tumor heterogeneity, turnover rate and karyotype space shape susceptibility to missegregation-induced extinction

G. J. Kimmel, R. J. Beck, X. Yu, T. Veith, S. Bakhoum, P. M. Altrock, N. Andor

The paper models chromosome missegregation in tumors to assess extinction risk, finding that intra-tumor heterogeneity and karyotype stability prevent extinction unless turnover rates are extremely high.

PLOS Computational Biology · Jan 23, 2023Peer-reviewedCancer Biology