R. J. Butler

Tozorakimab (MEDI3506): a dual-pharmacology anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction

This paper describes tozorakimab, an anti-IL-33 antibody that inhibits both reduced and oxidized IL-33 signaling pathways to reduce inflammation and epithelial dysfunction.

Early tetrapod diversification under neutral theory

This study uses a neutral theory model to show that early tetrapod diversity changes during the late Carboniferous and early Permian were not driven by local endemism but by sampling intensity variations.

A unique predator in a unique ecosystem: modelling the apex predator from the Late Cretaceous crocodyliform-dominated fauna in Brazil.

This study uses biomechanical modeling to analyze the predatory role of baurusuchids in Late Cretaceous Brazil, showing their unique adaptations as apex predators.

The multi-peak adaptive landscape of crocodylomorph body size evolution

This paper analyzes crocodylomorph body size evolution using model fitting, finding that multi-peak adaptive landscapes and lineage-specific adaptations better explain size changes than climatic factors.