Intracellular Delivery of Antibodies for Selective Cell Signaling Interference
R. L. Hershman, Y. Li, F. Ma, Q. Xu, J. A. Van Deventer
This paper demonstrates the use of cationic lipid nanoparticles to deliver engineered antibodies into cells, enabling selective disruption of intracellular signaling via pYSTAT3.
bioRxiv · Oct 5, 2021Bioengineering