The RNA binding protein hnRNP-U is required for physiological hypertrophy of skeletal muscle
D. Bagchi, B. D. Mason, K. Baldino, B. Li, E.-J. Lee, Y. Zhang, L. K. Chu, S. El Raheb, I. Sinha, R. L. Neppl
This study shows that hnRNP-U is essential for physiological skeletal muscle hypertrophy, as its deficiency leads to muscle wasting due to impaired autophagy and anabolic resistance.
bioRxiv · Feb 13, 2020Cell Biology