Mitochondrial Raf1 Regulates Glutamine Catabolism
R. L. Shanderson, I. D. Ferguson, Z. Siprashvili, L. Ducoli, A. Li, W. Miao, S. Srinivasan, M. G. Velasco, Y. Li, J. Ye, P. Khavari
This paper identifies Raf1 within mitochondria where it interacts with GLS to regulate glutamine catabolism and tumorigenesis, independent of MAPK signaling.
bioRxiv · Mar 8, 2024Cancer Biology