Estimating the Probability of Early Afterdepolarization and Predicting Arrhythmic Risk associated with Long QT Syndrome Type 1 Mutations
Q. Jin, J. L. Greenstein, R. L. Winslow
The paper develops a logistic regression model to estimate early afterdepolarization probability for LQTS1 mutations and compares it with two other risk metrics, finding similar performance but incomplete functional understanding of mutations.
bioRxiv · Apr 9, 2020 · PreprintBiophysics