Mice developing mammary tumors evolve T cell sequences shared with human breast cancer patients
M. Gordin, H. Philip, A. Zilberberg, M. Gidoni, R. Margalit, C. Clouser, K. Adams, F. Vigneault, I. R. Cohen, G. Yaari, S. Efroni
The paper tracks TCR repertoire evolution in mice with mammary tumors and finds shared tumor-exclusive TCR sequences with human breast cancer patients.
bioRxiv · Aug 6, 2018Cancer Biology