Author

R. Nepal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. J. Psaltis· 3 shared G. Bouras· 3 shared G. Houtak· 3 shared G. Shaghayegh· 3 shared P.-J. Wormald· 3 shared S. Vreugde· 3 shared C. Bennett· 1 shared C. Cooksley· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersMicrobiology

A. J. Psaltis

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Prophage acquisition by Staphylococcus aureus contributes to the expansion of Staphylococcal immune evasion

R. Nepal, G. Houtak, G. Bouras, M. Ramezanpour, S. Feizi, G. Shaghayegh, K. Shearwin, A. J. Psaltis, P.-J. Wormald, S. Vreugde

This study shows that acquisition of the {phi}Sa3int prophage by S. aureus alters its exoproteome, enhancing immune evasion and chronic infection potential.

bioRxiv · Apr 27, 2023Microbiology

Staphylococcus aureus biofilm secreted factors cause mucosal damage, mast cell infiltration and goblet cell hyperplasia in a rat rhinosinusitis model

G. Houtak, R. Nepal, G. Bouras, G. Shaghayegh, C. Bennett, J. Finnie, K. Fenix, A. J. Psaltis, P.-J. Wormald, S. Vreugde

This study shows that S. aureus biofilm secreted factors from CRS patients cause more severe mucosal inflammation in rats compared to controls.

bioRxiv · Mar 29, 2023 · PreprintImmunology

The Intra-Host Evolutionary Landscape And Pathoadaptation Of Persistent Staphylococcus aureus In Chronic Rhinosinusitis

G. Houtak, G. Bouras, R. Nepal, G. Shaghayegh, C. Cooksley, A. J. Psaltis, P.-J. Wormald, S. Vreugde

This study examines S. aureus persistence and pathoadaptation in CRS patients, finding 41% of isolates are persisters with increased biofilm biomass and plasmid copy numbers.

bioRxiv · Mar 28, 2023Microbiology