Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes
M. M. Temoche-Diaz, M. J. Shurtleff, R. M. Nottingham, J. Yao, R. P. Fadadu, A. M. Lambowitz, R. Schekman
The paper identifies distinct miRNA sorting mechanisms in cancer cell-derived extracellular vesicles, showing selective and non-selective pathways mediated by Lupus La and miR-122 motifs.
bioRxiv · Apr 17, 2019Biochemistry