Collagen content and cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of collagen cross-linking inhibitor beta-aminopropionitrile
S. E. Brashear, R. P. Wohlgemuth, L.-Y. R. Hu, E. H. Jbeily, B. A. Christiansen, L. R. Smith
This study investigates the effect of BAPN on collagen cross-linking and passive stiffness in dystrophic mdx mice, finding no reduction in cross-linking but a positive correlation between cross-linking and stiffness.
bioRxiv · Jul 8, 2022 · PreprintPhysiology