Author

R. Pachynski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:DNA methylation· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Borkowski· 1 shared B. Peng· 1 shared B. Van Tine· 1 shared D. Thorek· 1 shared E. Krug· 1 shared G. Virdi· 1 shared K. Kim· 1 shared K. Rennier· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Borkowski

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2 papers

Recent·Most cited

High dimensional analyses reveal activation of lymphocyte subsets and reversal of immunoresistance by cytokine enhancement of adoptive cellular vaccine therapy in prostate cancer.

M. Saeed, B. Peng, K. Kim, A. Borkowski, B. Van Tine, N. Sheikh, T. Vu, D. Thorek, T. Fehniger, R. Pachynski

This study shows IL-15 treatment enhances the anti-tumor efficacy of sipuleucel-T by increasing CD8+ T-cell and CD56+ NKT subset activity in prostate cancer.

bioRxiv · Jul 23, 2023 · PreprintImmunology

Chemerin increases T-cell mediated cytotoxicity of human tumors via modulation of a novel CMKLR1/PTEN/PD-L1 axis

K. Rennier, E. Krug, G. Virdi, W. J. Shin, R. Pachynski

This study shows chemerin enhances T-cell cytotoxicity against tumors by modulating the CMKLR1/PTEN/PD-L1 axis, with effects comparable to PD-L1 inhibition.

bioRxiv · Sep 30, 2019 · PreprintCancer Biology