Nitric Oxide modulates spontaneous Ca2+ release and ventricular arrhythmias during β adrenergic signalling through S-nitrosylation of Calcium/Calmodulin dependent kinase II
A. S. Power, E. Asamudo, L. P. Worthington, C. C. Alim, R. Parackal, R. S. Wallace, O. V. Ebenebe, J. Heller Brown, M. J. Kohr, D. M. Bers, J. Erickson
This study investigates how nitric oxide modulates calcium handling and arrhythmias via S-nitrosylation of CaMKIIδ at specific sites during β-adrenergic signaling.
bioRxiv · Aug 23, 2023 · PreprintPhysiology