Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts B cell growth
R. Ponnusamy, R. Khatri, P. B. Correia, E. Mancini, P. J. Farrell, M. J. West
This study identifies a third BS69 binding motif in type 2 EBNA2 that restricts B cell growth by enhancing EBNA2-BS69 interaction, explaining reduced transformation efficiency of type 2 EBV.
bioRxiv · Nov 7, 2018Microbiology