Mitochondrial Dysfunction is Part of a Novel Mechanism for Chemotherapy-Induced Neuropathic Pain
R. Sakas, S. Abu-Ata, Y. Nakhleh-Francis, N. Abd Elkarim, A. Kotiyal, H. Politte, Yaseen Awad-Igbaria, J. F. Soustiel, E. Palzur
This study identifies persistent spinal mitochondrial dysfunction and increased mPTP susceptibility as features of chemotherapy-induced neuropathic pain and supports mitochondrial protection as a therapeutic strategy.
bioRxiv · Nov 9, 2026 · PreprintNeuroscience