Cardiomyocyte cell cycling, maturation, and growth by multinucleation in postnatal swine
Nivedhitha Velayutham, Christina M. Alfieri, Emma J. Agnew, Kyle William Riggs, R. Scott Baker, Sithara Raju Ponny, Farhan Zafar, Katherine E. Yutzey
This study examines cardiac maturation in postnatal pigs and mice, finding that pig cardiomyocytes undergo multinucleation and growth dynamics distinct from mice, with cell cycle arrest and loss of mononucleated-diploid cells occurring later.
Journal of Molecular and Cellular Cardiology · Jul 22, 2020Peer-reviewedDevelopmental Biology